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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: RETRACTED ARTICLE: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression

Fig. 6

Effect of SSB extract on miR-124/Hedgehog and NF-κB65 signaling pathways in LPS-induced rat hepatocyte–KCs. Hepatocyte–KCs were incubated at various concentrations of SSB extract (1.0, 2, and 2.5 g/l) and LPS (1 mg/l) for 24 h. miR-124 expression was measured by RT-PCR. Hedgehog, Smo, Gli, p-Akt, and NF-κB65 protein levels were measured by Western blot. *P < 0.05 and **P < 0.01: compared with the control group; #P < 0.05 and ##P < 0.01 compared with the LPS group

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