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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Anti-allodynic effect induced by curcumin in neuropathic rat is mediated through the NO-cyclic-GMP-ATP sensitive K+ channels pathway

Fig. 1

The time course of the anti-allodynic effect following oral (a) and intrathecal (c) administration of curcumin (CUR) in rats who underwent to L5-L6 SNL. The withdrawal threshold was determined 14 days after surgery. The bars show the maximum possible effect (%MPE) (b and d). Data are expressed as mean ± S.E.M. of six animals. *P ≤ 0.05 versus SNL group and #P ≤ 0.05 versus sham group was determined by one-way ANOVA followed by Tukey test. &P ≤ 0.05 versus SNL group, determined by two-way repeated measures analysis of variance followed by the Bonferroni test. Abbreviations: GBP: Gabapentin, Veh: vehicle; SNL: spinal nerve ligation

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