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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and –independent apoptosis via Smad or Akt signaling pathways in HOS cells

Fig. 5

a The expression of full length caspase-3, cleaved caspase-3, full length PARP and cleaved PARP in HOS cells treated with 10–20 μΜ CUR, DMC, and BDMC for 24 h were detected using the western blotting assay. b Expression of p-Akt, p-p38, p-Erk 1/2, p-Smad2 and p-Smad 3 in HOS cells treated with 20 μΜ CUR, DMC, and BDMC for 4–8 h was detected using the western blotting assay

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