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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Investigating the multi-target pharmacological mechanism of danhong injection acting on unstable angina by combined network pharmacology and molecular docking

Fig. 4

Analysis of clusters and functional enrichment analysis. I: Clusters of the DHI-UA PPI network. (a) Module 1 (score = 16.375). (b) Module 2 (score = 5.000). (c) Module 3(score = 4.500). Red circles represent DHI-UA targets, and the remaining circles represent other human protein targets associated with disease treatment targets. II: GO enrichment analysis for each cluster. The top 10 GO terms were shown in the figure; p-value< 0.01 and q-value< 0.05; (d) GO enrichment analysis of Module 1. (e) GO enrichment analysis of Module 2. (f) GO enrichment analysis of Module 3. III: KEGG pathway enrichment analysis for each cluster. p-value< 0.05 and q-value< 0.05; (g): Pathway analysis of Module 1. (h) Pathway analysis of Module 2. (i) Pathway analysis of Module 3. The top 30 KEGG pathways were shown in the figure. The y-axis shows significantly enriched KEGG pathways, and x-axis shows the gene counts. (The software of Cytoscape 3.7.1 and R 3.6.1 were used to generate the figure)

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