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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Pharmacokinetic incompatibility of the Huanglian-Gancao herb pair

Fig. 1

Concentration-time curves of berberine in blood samples from the systemic circulation (a), portal vein (b), and the liver (c) of mice that received 0.88 g/kg oral Huanglian extract (HLE, 194 mg/kg berberine accordingly) or 2.00 g/kg Huanglian-Gancao extract (HL-GCE, 132 mg/kg berberine accordingly) (mean ± SD, n = 6). The HLE- and HL-GCE-treated groups were administered equal doses of the herb pieces of Huanglian (3 g/kg)

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