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Fig. 6 | BMC Complementary Medicine and Therapies

Fig. 6

From: Chaenomelis fructus inhibits osteoclast differentiation by suppressing NFATc1 expression and prevents ovariectomy-induced osteoporosis

Fig. 6

The effect of CF on OVX-induced osteoporosis rats. A Weights of rats were measured weekly, and the rats were sacrificed after weighing the B uterus and C femur. D Femur bone density was measured using Archimedes’ principle. CF treatment suppressed the bone metabolism indicator of OVX-induced rats in serum. E serum TRAP activity; F ALP; G ALT; H AST. Data represent as mean ± SEM (n = 8). ##P < 0.01 compared with sham and **P < 0.01, *P < 0.05 compared with OVX. TRAP, tartrate-resistant acid phosphatase; ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate aminotransferase; Sham, sham-operated and vehicle-treated group; OVX, bilateral-ovariectomized and vehicle-treated group; E2, bilateral-ovariectomized and 17β-estradiol-treated group; CF-L, bilateral-ovariectomized and low-dose of Chaenomelis fructus-treated group (35 mg/kg); CF-H, high-dose of bilateral-ovariectomized and Chaenomelis fructus-treated group (350 mg/kg)

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