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Table 2 Docking scores of blood bioactive ingredients of GFWE and LY294002 to PTEN/MTDH

From: Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract

CompoundsDocking Scores (pKd/pKi)
MTDHPTEN
Cinnamic acid3.062.82
Paeonol3.783.90
LY2940024.474.02
Benzoic acid5.674.96
Prunasin5.735.59
Albiflorin6.145.98
Protocatechuic acid6.145.18
Amygdalin6.185.33
Paeoniflorin6.266.21
Gallic acid6.425.43
Catechin6.996.16
Tumulosic acid7.957.67
Polyporenic acid C8.017.68
Dehydrotumulosic acid8.046.21
Poricoic acid B8.167.46
Eburicoic acid8.168.02
3-Dehydrotrametenolic acid8.178.08
  1. Note: The docking score represents the weak to strong binding activity ranging from 0 to 10