Table 2 Clearance rate parameters determined by WWARN’s Parasite clearance estimator
Measure | Group (N = 5) | Mean ± SD | t | P |
|---|---|---|---|---|
Lag time (hour) | A/LU (28 mg/kg A/LU) | 14.4 ± 10.04 | 1.78 | 0.117 |
Combination | 4.8 ± 6.57 | |||
Clearance rate constant / hour | A/LU (28 mg/kg A/LU) | 0.109 ± 0.03 | 0.084 | 0.936 |
Combination | 0.107 ± 0.02 | |||
Intercept lag time (hour) | A/LU (28 mg/kg A/LU) | 14.18 ± 0.75 | −0.076 | 0.942 |
Combination | 14.23 ± 1.2 | |||
Slope half-life (hour) | A/LU (28 mg/kg A/LU) | 6.88 ± 2.25 | −0.244 | 0.815 |
Combination | 6.61 ± 1.17 | |||
R2 | A/LU (28 mg/kg A/LU) | −12.9 ± 23.73 | −0.649 | 0.55 |
Combination | −5.92 ± 3.8 | |||
Est. time to clear 50% (hour) | A/LU (28 mg/kg A/LU) | 41.3 ± 16.91 | 0.619 | 0.556 |
Combination | 36.8 ± 10.22 | |||
Est. time to clear 99% (hour) | A/LU (28 mg/kg A/LU) | 64.2 ± 24.37 | 0.43 | 0.681 |
Combination | 58.8 ± 14.08 |