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Table 4 Inhibitory concentrations and therapeutic index of plant extracts against Laboratory adapted HIV-1IIIB and HIV-1Ada5 strains in TZM-bl cell lines

From: In vitro anti-HIV activity of some Indian medicinal plant extracts

Sr. No.

Plant Extract

CC50 (μg/ml)

IC50

IC80

Therapeutic Index

CF

CA

CF

CA

CF

CA

IIIB

Ada5

IIIB

Ada5

IIIB

Ada5

IIIB

Ada5

IIIB

Ada5

IIIB

Ada5

1

A. lebbeck

203

No activity

2

T. procumbens

62

No activity

3

A. aspera

69

8.3

2.3

4.1

28.4

18

21

26

35

14

35

13

3

4

F. benghalensis

72

6

6

5.2

2.25

9.6

9.6

8.32

3.6

12

12

14

32

5

M. philippinensis

71

No activity

6

R. centifolia

132

13.6

24.8

51.9

75.4

30.4

45.2

96.1

118

5

6

1

1

7

S. potatorum

124

4.97

3.65

18.51

17.67

29.17

35.89

79.35

78.43

10

24

8

7

8

A. reticulata

11

No activity

9

F. infectoria

147

1.18

2.97

4.97

87.38

4.24

8.6

52.49

> 125

189

49

27

2

10

A. squamosa

51

No activity

23

11.3

No activity

27

20

2

4

2

3

  1. CC50−50% cytotoxic concentration, IC50–50% inhibitory concentration
  2. IC80−80% inhibitory concentration, CF- Cell Free, CA- Cell Associated