Table 3 HB disease PPI network cluster analysis
From: Network pharmacology-based study on the mechanism of Yiganling capsule in hepatitis B treatment
Cluster | Score | Nodes | Edges | Node |
|---|---|---|---|---|
1 | 5.556 | 19 | 50 | HCK, SRC, PLCG1, IKBKE, PSMB9, PSMA3, PSMA7, CHUK, AIRE, IKBKB, PSMB8, PSMB5, FASLG, IKBKG, MET, TNF, AR, TNFAIP3, PSMD1 |
2 | 4 | 15 | 28 | HLA-E, HLA-B, HLA-C, CD8A, PTK2B, KRT18, KRT8, EGFR, CXCR4, IFNAR1, FYN, PIK3R1, SOCS1, CCR5, HLA-A |
3 | 3.333 | 13 | 20 | SRPK2, CEBPB, MOV10, IGF2BP1, CEBPA, CD81, HNRNPA1, HIST1H1E, ICAM1, DDX3X, NOLC1, VDR, SRPK1 |
4 | 3 | 7 | 9 | CUL5, KRT19, NFKB1, ESR1, TP53, FN1, HNRNPK |
5 | 3 | 5 | 6 | YWHAE, NPM1, GLTSCR2, C1QBP, PUM3 |
6 | 2.857 | 8 | 10 | VIM, CDK1, BECN1, EIF2AK2, GFAP, PML, JAK1, HMGB1 |