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Table 9 Effect of CEDL pretreatment on the endogenous antioxidant enzyme system activity, namely CAT and SOD, in the liver of PCM-induced liver intoxication in rats

From: Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat

Treatment Dose (mg/kg) CAT (U/g tissue) SOD (U/g tissue)
Normal 201.6 ± 10.7 167.2 ± 8.1
Negative 92.4 ± 8.1a 82.6 ± 9.7a
Positive 50 151.6 ± 9.7ab 129.3 ± 6.6ab
CEDL 50 96.3 ± 8.8a 91.9 ± 9.2a
250 129.6 ± 5.2 ab 122.1 ± 4.9ab
500 193.3 ± 5.8ab 152.6 ± 6.9ab
  1. Normal – Group pretreated and treated with vehicle only; Negative – Group pretreated with vehicle and treated with PCM; Positive – Group pretreated with NAC and treated with PCM; CEDL – Group pretreated with CEDL and treated with PCM
  2. Values are expressed as means ± SEM of six replicates
  3. a Data differed significantly (p < 0.05) when compared against the normal group
  4. b Data differed significantly (p < 0.05) when compared against the negative control group
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