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Table 7 Tissue inflammation scoring of PCM-intoxicated rat’s liver following the oral treatment with vehicle (10% DMSO), 50 mg/kg NAC or, 50, 250 and 500 mg/kg CEDL in comparison to the normal tissue

From: Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat

Group Dose Number of animals Severity score of tissue inflammation Mean ± SEM
mg/kg n 0 1 2 3
Normal 6 6 0 0 0 0
Negative 6 0 0 1 5 2.83 ± 0.17
Positive 50 6 3 3 0 0 0.50 ± 0.22***
CEDL 50 6 0 0 0 6 3.00 ± 0.00
250 6 4 2 0 0 0.33 ± 0.21***
500 6 5 1 0 0 0.17 ± 0.17***
  1. Note: The severity score of tissue inflammation was expressed as Mean ± SEM for 6 animals. One-way ANOVA was followed by Dunnett’s post-hoc test, ***p < 0.001 vs. vehicle
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