Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat

Table 5 Effect of CEDL, in the dose range of 50 to 500 mg/kg, on the body and liver weights, and liver/body weight ratio of PCM-intoxicated rats

Treatment	Dose (mg/kg)	Body weight (BW) (g)	Liver weight (LW) (g)	LW/BW (%)
Normal	–	204.3 ± 3.2	6.1 ± 0.7	2.99
Negative	–	206.2 ± 4.9	9.1 ± 0.2^a	4.41^a
Positive	50	204.9 ± 6.6	6.4 ± 0.5^b	3.12^b
CEDL	50	201.7 ± 4.2	8.0 ± 1.1	3.97
	250	204.4 ± 5.1	7.1 ± 0.1^b	3.47^b
	500	202.8 ± 6.3	6.0 ± 0.6^b	2.96^b

Normal – Group pretreated and treated with vehicle only; Negative – Group pretreated with vehicle and treated with PCM; Positive – Group pretreated with NAC and treated with PCM; CEDL – Group pretreated with CEDL and treated with PCM
^a Data differed significantly (p < 0.05) when compared against the normal group
^b Data differed significantly (p < 0.05) when compared against the negative control group

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