Skip to main content

Table 5 Effect of CEDL, in the dose range of 50 to 500 mg/kg, on the body and liver weights, and liver/body weight ratio of PCM-intoxicated rats

From: Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat

Treatment Dose (mg/kg) Body weight (BW) (g) Liver weight (LW) (g) LW/BW (%)
Normal 204.3 ± 3.2 6.1 ± 0.7 2.99
Negative 206.2 ± 4.9 9.1 ± 0.2a 4.41a
Positive 50 204.9 ± 6.6 6.4 ± 0.5b 3.12b
CEDL 50 201.7 ± 4.2 8.0 ± 1.1 3.97
250 204.4 ± 5.1 7.1 ± 0.1b 3.47b
500 202.8 ± 6.3 6.0 ± 0.6b 2.96b
  1. Normal – Group pretreated and treated with vehicle only; Negative – Group pretreated with vehicle and treated with PCM; Positive – Group pretreated with NAC and treated with PCM; CEDL – Group pretreated with CEDL and treated with PCM
  2. a Data differed significantly (p < 0.05) when compared against the normal group
  3. b Data differed significantly (p < 0.05) when compared against the negative control group