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Table 5 Metabolic parameters of the control and tumor groups treated with saline (CS and TS) or 200 mg/kg Fr-BuVt (CV200 and TV200)

From: Vochysia tucanorum Mart. butanol fraction presents antitumoral activity in vivo and prevents the installation of cachexia in solid Ehrlich tumor model

  CS CV200 TS TV200
Initial glycaemia (mg/dL) 80.3 ± 1.7 79.0 ± 3.2 82.4 ± 1.4 81.1 ± 2.0
Final glycaemia (mg/dL) 80.0 ± 4.4 77.5 ± 4.4 59.4 ± 2.9 * 81.7 ± 4.0 $
Triglycerides (mg/dL) 107.0 ± 5.0 97.6 ± 4.3 189.7 ± 10.6 * 106.2 ± 5.9 $
FFA (mEq/L) 0.55 ± 0.06 0.42 ± 0.02 * 0.81 ± 0.04 * 0.56 ± 0.05 $
Total cholesterol (mg/dL) 121.5 ± 4.6 120.1 ± 5.9 101.3 ± 5.5 * 118.7 ± 3.2 $
HDL cholesterol (mg/dL) 74.6 ± 2.8 82.2 ± 2.9 52.9 ± 1.3 * 70.6 ± 3.8 $ &
ALT (U/L) 79.1 ± 3.8 73.2 ± 6.7 144.1 ± 8.7 * 81.0 ± 4.06 $
AST (U/L) 286.1 ± 20.2 299.2 ± 24.0 439.0 ± 22.2 * 281.1 ± 16.1 $
Total proteins (g/dL) 6.1 ± 0.1 5.8 ± 0.3 5.1 ± 0.1 * 5.9 ± 0.1 $
Albumin (g/dL) 1.8 ± 0.05 1.92 ± 0.08 1.4 ± 0.05 * 1.7 ± 0.05 $
Lactate (mmol/L) 9.5 ± 0.5 9.28 ± 0.65 12.5 ± 0.9 * 9.4 ± 0.4 $
Hepatic glycogen (g/100 g) 2.9 ± 0.3 2.5 ± 0.4 0.34 ± 0.04 * 2.5 ± 0.2 $
Muscle glycogen (g/100 g) 0.81 ± 0.06 0.85 ± 0.09 0.44 ± 0.07 * 0.68 ± 0.06 $
TNF-α 1.18 ± 0.2 1.0 ± 0.1 9.7 ± 0.9 * 1.6 ± 0.2 $
IL-6 3.4 ± 0.4 3.0 ± 0.5 22.5 ± 0.7* 4.0 ± 0.4 $
  1. Values are expressed as means ± SEM, two-way ANOVA followed by Holm-Sidak post hoc test, p < 0.05 (* vs CS; $ vs TS; & vs CV).