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Table 5 Metabolic parameters of the control and tumor groups treated with saline (CS and TS) or 200 mg/kg Fr-BuVt (CV200 and TV200)

From: Vochysia tucanorum Mart. butanol fraction presents antitumoral activity in vivo and prevents the installation of cachexia in solid Ehrlich tumor model

 

CS

CV200

TS

TV200

Initial glycaemia (mg/dL)

80.3 ± 1.7

79.0 ± 3.2

82.4 ± 1.4

81.1 ± 2.0

Final glycaemia (mg/dL)

80.0 ± 4.4

77.5 ± 4.4

59.4 ± 2.9 *

81.7 ± 4.0 $

Triglycerides (mg/dL)

107.0 ± 5.0

97.6 ± 4.3

189.7 ± 10.6 *

106.2 ± 5.9 $

FFA (mEq/L)

0.55 ± 0.06

0.42 ± 0.02 *

0.81 ± 0.04 *

0.56 ± 0.05 $

Total cholesterol (mg/dL)

121.5 ± 4.6

120.1 ± 5.9

101.3 ± 5.5 *

118.7 ± 3.2 $

HDL cholesterol (mg/dL)

74.6 ± 2.8

82.2 ± 2.9

52.9 ± 1.3 *

70.6 ± 3.8 $ &

ALT (U/L)

79.1 ± 3.8

73.2 ± 6.7

144.1 ± 8.7 *

81.0 ± 4.06 $

AST (U/L)

286.1 ± 20.2

299.2 ± 24.0

439.0 ± 22.2 *

281.1 ± 16.1 $

Total proteins (g/dL)

6.1 ± 0.1

5.8 ± 0.3

5.1 ± 0.1 *

5.9 ± 0.1 $

Albumin (g/dL)

1.8 ± 0.05

1.92 ± 0.08

1.4 ± 0.05 *

1.7 ± 0.05 $

Lactate (mmol/L)

9.5 ± 0.5

9.28 ± 0.65

12.5 ± 0.9 *

9.4 ± 0.4 $

Hepatic glycogen (g/100 g)

2.9 ± 0.3

2.5 ± 0.4

0.34 ± 0.04 *

2.5 ± 0.2 $

Muscle glycogen (g/100 g)

0.81 ± 0.06

0.85 ± 0.09

0.44 ± 0.07 *

0.68 ± 0.06 $

TNF-α

1.18 ± 0.2

1.0 ± 0.1

9.7 ± 0.9 *

1.6 ± 0.2 $

IL-6

3.4 ± 0.4

3.0 ± 0.5

22.5 ± 0.7*

4.0 ± 0.4 $

  1. Values are expressed as means ± SEM, two-way ANOVA followed by Holm-Sidak post hoc test, p < 0.05 (* vs CS; $ vs TS; & vs CV).