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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Norwogonin attenuates hypoxia-induced oxidative stress and apoptosis in PC12 cells

Fig. 4

Norwogonin down-regulated the expression of HIF-1α and VEGF in PC12 cells following hypoxia exposure. Cells were incubated with norwogonin for 1 h and then exposed to hypoxia for 24 h. The mRNA expression was determined by the real-time qPCR (a). The expressions of HIF-1α and VEGF proteins were detected using Western blot analysis (b). In order to improve the clarity and conciseness of the presentation, the blots were cropped. Statistical analysis results of HIF-1α (c) and VEGF (d) from Western blot analysis. Results are expressed as means ± SD, n = 3. ##P < 0.01 vs control group, *P < 0.05, **P < 0.01 vs hypoxia group

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