Table 4 Effects of male treatment with PADE on fetal development
Parameters | Study groupsa | ||
|---|---|---|---|
Control, H2O | PADE, 25 mg/kg | PADE, 125 mg/kg | |
Fetal development on day 20 post fertilization (mean + SD) | |||
No. of dams examined | 5 | 8 | 8 |
No. corpus luteum/dam | 12.6 + 0.7 | 11.3 + 0.8 | 12.3 + 0.6 |
No. implantations/dam | 11.0 + 0.8 | 9.9 + 0.6 | 10.5 + 0.6 |
No. live fetuses/dam | 10.2 + 0.7 | 9.0 + 0.3 | 9.9 + 0.8 |
No. resorptions/ dam | 0.8 + 0.3 | 0.9 + 0.5 | 0.6 + 0.3 |
Fetal weight, (g) | 2.4 + 0.1 | 2.3 + 0.1 | 2.3 + 0.1 |
Pre-implantation death (%) | 12.7 | 12.4 | 14.6 |
Post-implantation death (%) | 7.3 | 9.1 | 5.7 |