Table 2 PADE gonadotropic effects
Parameters | Study groupsa | ||
|---|---|---|---|
Control | PADE, 25 mg/kg | PADE, 125 mg/kg | |
Total number of spermatozoa (× 106) | 591.1+ 37.2 | 599.4 + 35.5 | 481.2 + 54.5 |
Motile spermatozoa (×106) | 327.8 + 18.6 | 240.6 + 26.6** | 163.3 + 29.1** |
Motile spermatozoa (%) | 56.1 + 2.9 | 46.3 + 1.7** | 32.8 + 3.3** |
Duration of spermatozoon movement (min.) | 170.0 + 13.5 | 162.5 + 16.0 | 98.0 + 11.4** |
Pathologic forms of spermatozoa (%) | 1.5+ 0.3 | 2.7 + 0.2** | 5.1 + 0.5** |
Testicular weight (g) | 3.2 + 0.1 | 3.3 + 0.1 | 3.4 + 0.2 |
Relative testicular weight (%) | 0.76 + 0.04 | 0.82 + 0.02 | 0.90 + 0.04 |
Spermatogenesis index, Median (range) | 3.36 (3.28,3.42) | 3.08 (3.04,3.11) ** | 3.02 (3.0,3.05) ** |