Fig. 4

Renal function impairment and pathological lesions were alleviated by SK on the 14th day of treatment. a Levels of Cys-C (n = 6); b levels of BUN (n = 6); c levels of SCr (n = 6); d representative images of histopathological manifestations in obstructed kidneys detected on the 14th day (HE staining, 200×). The data are presented as the mean ± SEM; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 versus the sham group; *P < 0.05, **P < 0.01, ***P < 0.001 versus the UUO group (A = sham group, B = UUO group, C = ARB group, D = low-dose SK group, E = moderate-dose SK group, F = high-dose SK group)