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Table 3 The topological parameters of target genes sorted by degree

From: Systematic elucidation of the pharmacological mechanisms of Rhynchophylline for treating epilepsy via network pharmacology

Target genes

Degree

Closeness

Betweenness

ADORA1

14

0.557

0.119

OPRM1

12

0.527

0.069

OPRD1

11

0.513

0.051

PDE2A

10

0.5

0.075

OPRK1

10

0.5

0.039

ADRB1

8

0.476

0.043

PDE9A

7

0.464

0.038

PDE10A

7

0.464

0.033

PDE8B

7

0.464

0.029

CHRNA4

7

0.464

0.016

MAOB

6

0.453

0.037

CA2

6

0.453

0.034

CACNA1G

6

0.453

0.008

SCN5A

6

0.453

0.008

PDE1C

5

0.443

0.019

SLC6A4

5

0.443

0.004

CA12

4

0.433

0.021

PIK3CA

4

0.433

0.011

MAOA

3

0.424

0.017

ATM

2

0.415

0