Fig. 6

GM induced anti-oxidative and anti-inflammatory responses via regulating Nrf2 and NF-κB pathways. In each group, the protein levels of Nrf2 and NF-κB p-p65 in brain tissue of CCI mice were detected by Western blot assay. Sham: Control group; CCI: TBI model group; CCI + GM 5 mg/kg: CCI mice treated with 5 mg/kg GM group; CCI + GM 10 mg/kg: CCI mice treated with 10 mg/kg GM group; CCI + GM 20 mg/kg: CCI mice treated with 20 mg/kg GM group; * P < 0.05, ** P < 0.01 and *** P < 0.001 versus the sham group; ## P < 0.01 and ### P < 0.001 versus the CCI group