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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress

Fig. 4

GM increased the expression level of pro-inflammatory cytokines in CCI-treated mice. a-c qRT-PCR assay was used to detect the relative expressions of inflammatory factors TNF-α, IL-1β and IL-6 mRNA in the brain tissue of mice in each group. d-f ELISA kit was used to detect the contents of inflammatory factors TNF-α, IL-1β and IL-6 in the brain tissue of mice in each group. Sham: Control group; CCI: TBI model group; CCI + GM 5 mg/kg: CCI mice treated with 5 mg/kg GM group; CCI + GM 10 mg/kg: CCI mice treated with 10 mg/kg GM group; CCI + GM 20 mg/kg: CCI mice treated with 20 mg/kg GM group; * P < 0.05, ** P < 0.01 and *** P < 0.001 versus the sham group. # P < 0.05, ## P < 0.01 and ### P < 0.001 versus the CCI group

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