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Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress

Fig. 2

GM ameliorated the brain injury caused by CCI in mice. a Rota-rod test was used to test the motor function of mice in each group. b, c Morris water maze test was used to detect the spatial learning and memory functions of mice in each group. d The brain tissue of mice in each group was examined with HE staining (left) and brain edema was measured by dry-wet method (right). (Bar = 50 μm). e The brain tissue of mice was stained with Nissl staining solution and the number of abnormal Nissl body was counted. (Bar = 50 μm). Sham: Control group; CCI: TBI model group; CCI + GM 5 mg/kg: CCI mice treated with 5 mg/kg GM group; CCI + GM 10 mg/kg: CCI mice treated with 10 mg/kg GM group; CCI + GM 20 mg/kg: CCI mice treated with 20 mg/kg GM group; * P < 0.05, ** P < 0.01 and *** P < 0.001 versus the Sham group; # P < 0.05, ## P < 0.01 and ### P < 0.001 versus the CCI group

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