Table 3 Notable targets after network analysis
Share Name | Common Name | PDB Code | Binding Molecule | Related pathway |
|---|---|---|---|---|
HMGCR | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1DQ8 | baicalin; wogonoside | AMPK signaling pathway |
HNF4A | Hepatocyte nuclear factor 4-alpha | 3FS1 | baicalin; wogonoside | AMPK signaling pathway |
SIRT1 | NAD-dependent protein deacetylase sirtuin-1 | 4ZZI | morroniside; loganin; baicalin; wogonoside; sweroside | AMPK signaling pathway |
JAK3 | Tyrosine-protein kinase Janus kinase 3 | 3LXL | baicalin; wogonoside | PI3K-Akt signaling pathway |