|
Bacterial strains
|
Tested samples and concentrations (μg/mL)
|
|---|
|
CSB
|
CSBc
|
CSBc1
|
CSBc2
|
CSBc3
|
Chloramphenicol
|
|---|
|
MIC
|
+PAβN
|
R
|
MIC
|
+PAβN
|
R
|
MIC
|
+PAβN
|
R
|
MIC
|
+PAβN
|
R
|
MIC
|
+PAβN
|
R
|
MIC
|
+PAβN
|
R
|
|---|
|
Escherichia coli
|
|
ATCC8739
|
512
|
64
|
8
|
512
|
16
|
32
|
256
|
16
|
16
|
256
|
64
|
4
|
256
|
256
|
1
|
2
|
< 0,5
|
> 4
|
|
AG102
|
512
|
64
|
8
|
512
|
32
|
16
|
–
|
–
|
nd
|
256
|
< 4
|
> 64
|
64
|
–
|
> 8
|
32
|
4
|
8
|
|
Klebsiella pneumoniae
|
|
ATCC11296
|
512
|
–
|
< 1
|
512
|
128
|
4
|
64
|
16
|
4
|
256
|
128
|
2
|
–
|
< 4
|
> 128
|
32
|
8
|
4
|
|
KP55
|
128
|
< 4
|
> 32
|
128
|
256
|
0.5
|
–
|
–
|
nd
|
–
|
256
|
> 2
|
–
|
–
|
nd
|
64
|
32
|
2
|
|
Enterobacter aerogenes
|
|
ATCC13048
|
512
|
16
|
32
|
512
|
256
|
2
|
512
|
–
|
< 1
|
256
|
32
|
8
|
–
|
< 4
|
> 128
|
16
|
32
|
2
|
|
EA27
|
–
|
32
|
> 16
|
–
|
< 4
|
128
|
–
|
64
|
> 8
|
–
|
256
|
> 2
|
–
|
–
|
nd
|
32
|
16
|
2
|
|
Providencia stuartii
|
|
ATCC29916
|
512
|
32
|
16
|
512
|
256
|
2
|
–
|
–
|
nd
|
256
|
128
|
2
|
256
|
8
|
32
|
64
|
8
|
8
|
|
PS2636
|
512
|
32
|
16
|
512
|
128
|
4
|
–
|
–
|
nd
|
256
|
–
|
< 2
|
–
|
–
|
nd
|
64
|
16
|
4
|
|
Pseudomonas aeruginosa
|
|
PA01
|
512
|
–
|
nd
|
512
|
–
|
< 1
|
–
|
–
|
nd
|
–
|
–
|
nd
|
–
|
< 4
|
> 128
|
64
|
8
|
8
|
|
PA124
|
512
|
–
|
nd
|
512
|
256
|
2
|
–
|
–
|
nd
|
128
|
256
|
0,5
|
–
|
16
|
> 32
|
256
|
16
|
16
|
|
PIA (%)
| |
70
| | |
80
| | |
30
| | |
70
| | |
60
| | |
100
| |
- MIC minimal inhibitory concentration R = AIF: MICample alone / MICample+PAβN ratio (this means the factor which determine the improvement of the activity of samples by PAβN; the activity of a sample was considered to be improved when its AIF was > 2). (+ PAβN): represent MIC values of tested samples obtained in presence of PAβN (−): MIC > 512 μg/mL for crude extract, fractions and sub-fractions PIA: percentage of improved activity nd: not determined (as no MIC values were not observed till 512 μg/mL) CSB: crude extract CSBc: fraction CSBc1, CSBc2 and CSBc3 are sub-fractions from fraction CSBc
