Fig. 4From: The in vitro and in vivo wound-healing effects of royal jelly derived from Apis mellifera L. during blossom seasons of Castanea mollissima Bl. and Brassica napus L. in South China exhibited distinct patternsEffects of royal jelly extracts on the cell viability and LPS-induced mediators production in murine macrophages. a Cytotoxic effects of hydrophilic extracts from Castanea mollissima Bl. royal jelly on RAW 264.7 cells as determined by MTT assay. *, p < 0.05; **, p < 0.01; ***, p < 0.001, compared with control. Effects of royal jelly extracts on the production of NO (b), TNF-α (c) and TGF-β1 (d) in LPS-induced RAW 264.7 cells. CmRJ-Zj-HE, hydrophilic extracts from Castanea mollissima Bl. royal jelly; CmRJ-Zj-LE, lipophilic extracts from Castanea mollissima Bl. royal jelly; BnRJ-Zj-HE, hydrophilic extracts from Brassica napus L. royal jelly; BnRJ-Zj-LE, lipophilic extracts from Brassica napus L. royal jelly. Results are expressed as the mean ± SEM. ###, p < 0.001, compared with control (vehicle treated cells). *, p < 0.05; **, p < 0.01; ***, p < 0.001, compared with LPS-stimulated cellsBack to article page