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Fig. 4 | BMC Complementary Medicine and Therapies

Fig. 4

From: Twenty-four-week oral dosing toxicities of Herba Siegesbeckiae in rats

Fig. 4

HSE caused oxidative stress, and induced the activation of MAPKs in lung tissues of rats. Animal treatments are the same as in Fig. 1. a Levels of MDA, and activities of GSH-PX, CAT and SOD in lung tissues. Values are expressed as mean ± SEM (n = 20). b Protein levels of p38, phospho-p38 (Thr180/Tyr182), JNK, phospho-JNK (Thr183/Tyr185), ERK and phospho-ERK (Thr202/Tyr204). α-Actinin served as a loading control. Representative immunoblotting results (left panel) and quantitative results (right panel) are shown. Data in bar charts are mean ± SEM of 3 independent experiments. In (a) and (b), * P < 0.05, ** P < 0.01 vs. control group

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