Fig. 2
From: Twenty-four-week oral dosing toxicities of Herba Siegesbeckiae in rats
HSE elevated relative liver and lung weights, and induced histopathological alterations in liver and lung tissues. Animal treatments are the same as in Fig. 1. a Relative liver weight of rats. b Relative lung weight of rats. Values are expressed as mean ± SEM (n = 10). * P < 0.05 vs. control group of male rats. # P < 0.05 vs. control group of female rats. c H&E staining of liver tissues. Representative photos of H&E staining of liver tissues are shown. Inflammatory cells (arrows), bile duct (squares), and portal vein (PV) are pointed. Scale bars: 50 μm. d H&E staining of lung tissues. Representative photos of H&E staining of lung tissues are shown. Inflammatory cells (arrows) and alveoli (squares) are pointed. Scale bars: 100 μm