Fig. 1From: Jianpi Yangwei decoction promotes apoptosis and suppresses proliferation of 5-fluorouracil resistant gastric cancer cells in vitro and in vivoJPYW induced BGC823 cells apoptosis. a. MTT assay showed a dose-dependent cell proliferation inhibition of JPYW on BGC823 cells; b. Staining with Hoechst 33342, the control BGC823 cells showed normal nuclear morphology, and few apoptotic cells with nuclear condensation. The cells treated with JPYW showed increased number of apoptotic cells with obvious cytoplasmic wrinkling and nuclear edge aggregation, and formed obvious lunate corpuscles. (Magnification 400×); c. Flow cytometry showed that, following treatment with JPYW at 8 mg/ml, the percentage of apoptotic cells was found significantly increased as compared with the control groupBack to article page