Fig. 4

Effect of HESAE on endogenous antioxidant enzyme activities in PC-12 cells treated with high-dose corticosterone. a SOD, b CAT and c GPx activities were evaluated by SOD, CAT and GPx assays following pre-treatment with HESAE for 48 h and high-dose corticosterone of 400 μM for 24 h. Data are expressed as mean ± SD and statistically analysed by Tukey’s test. Asterisks (*) and hash signs (#) indicate significant differences (p < 0.05) in SOD, CAT and GPx activities compared to the corticosterone group and desipramine group, respectively