Fig. 9

EAB extract significantly reduces cell migration. EAB extract at 100 μg/ml (d) and 50 μg/ml (c) inhibited migration of highly metastatic prostate cancer cells PC-3 cells compared to untreated control (a) and cells treated with solvent ethyl acetate (b). Cells were seeded into 6-well plates for 24 h after which each well was scratched at image captured at 0 h, treated and incubated for another 24 h where images were subsequently captured to demonstrate the extent of migration. The maintenance of a larger denude (visually) in the EAB treated groups indicate the lowered levels of cell migration (quantitated). Statistical significance indicated by ** indicating a p-value < 0.001 (one-way ANOVA)