TY - JOUR AU - Foster, Kimberley AU - Oyenihi, Omolola AU - Rademan, Sunelle AU - Erhabor, Joseph AU - Matsabisa, Motlalepula AU - Barker, James AU - Langat, Moses K. AU - Kendal-Smith, Amy AU - Asemota, Helen AU - Delgoda, Rupika PY - 2020 DA - 2020/12/10 TI - Selective cytotoxic and anti-metastatic activity in DU-145 prostate cancer cells induced by Annona muricata L. bark extract and phytochemical, annonacin JO - BMC Complementary Medicine and Therapies SP - 375 VL - 20 IS - 1 AB - Annona muricata L. was identified as a popular medicinal plant in treatment regimens among cancer patients in Jamaica by a previously conducted structured questionnaire. Ethnomedically used plant parts, were examined in this study against human prostate cancer cells for the first time and mechanisms of action elucidated for the most potent of them, along with the active phytochemical, annonacin. SN - 2662-7671 UR - https://doi.org/10.1186/s12906-020-03130-z DO - 10.1186/s12906-020-03130-z ID - Foster2020 ER -