Fig. 5
From: Anticancer activity of Momordica cochinchinensis (red gac) aril and the impact of varietal diversity
Ultrastructure analysis of breast cancer and melanoma cell lines treated with M. cochinchinensis aril water extract (2 mg/mL). a-c: Control (a) and 2 mg/mL treated MCF7 cells with morphological alterations at 72 h. d-i: Control (d, g) and 2 mg/ml treated MM418C1 (e-f) and D24 (h-i) melanoma cells with apoptotic and necrotic cell death. Solid-line arrow: Chromatin condensation. Dotted-line arrow: Margination of chromatin. Hatched-line arrow: Vacuolisation. Double-line arrow: Cell membrane blebbing. NU: Nucleus, NM: Nuclear membrane, PM: Plasma membrane