Fig. 5

Effect of AC extract on BDNF and TrkB expression in OVX rats with CUMS exposure. a The levels of BDNF and TrkB expression in hippocampus of rats were measured by western blotting. AC extract administration restored BDNF and TrkB expression in OVX rats with CUMS exposure. Western blots show expression levels of BDNF and TrkB in hippocampus of rats. b, c Quantification of proteins shown in (a). The relative levels of the proteins were normalized to β-actin expression. The band intensities were measured using Image J. N = 3 independent ELISA from 5 rats for each experimental group. Data represent mean ± SEM. Statistical significance was determined by multiple t-test with Bonferonni correction test. **P < 0.01, ***P < 0.001