Fig. 4

Effect of AC extract on serum corticosterone and pro-cytokines levels in OVX rats with CUMS exposure. a The level of serum corticosterone in rats was measured after AC extract treatment. AC extract administration suppressed serum corticosterone level in OVX rats with CUMS exposure. N = 5 independent ELISA from 5 rats for each experimental group. Data represent mean ± SEM. Statistical significance was determined by multiple t-test with Bonferonni correction test. *P < 0.05, **P < 0.01, ***P < 0.001. b, c, d The levels of serum pro-cytokines in rats were measured after AC extract treatment. AC extract administration suppressed serum TNF-α, IL-1β, IL-6 levels in OVX rats with CUMS exposure. N = 5 independent ELISA from 5 rats for each experimental group. Data represent mean ± SEM. Statistical significance was determined by multiple t-test with Bonferonni correction test. *P < 0.05, **P < 0.01, ***P < 0.001