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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Asparagus cochinchinensis extract ameliorates menopausal depression in ovariectomized rats under chronic unpredictable mild stress

Fig. 1

Effect of AC extract on body weight and food intake in OVX rats with CUMS exposure. a Schematic of the experimental design and group. Rats induce menopause by OVX. After recovery, the CUMS groups of animals received chronic unpredictable mild stress (CUMS) for 42 days. After 2 weeks of initial CUMS exposure, rats received AC extract or imipramine for 4 weeks. Subsequently, rats were evaluated depression-like behavior and biochemical analysis. b The effects of AC extract on body weight of rats. The body weight was measured once a week. N = 12 rats for each experimental group. Data represent mean ± SEM. Statistical significance was determined by multiple t-test with Bonferonni correction test. *P < 0.05, ***P < 0.001. c The ratio of in body weight gain (Δweight = Final body weight - Initial body weight). OVX increase body weight in rats, however, the body weight gain decreased in OVX rats after 6 weeks of CUMS exposure. N = 12 rats for each experimental group. Statistical significance was determined by multiple t-test with Bonferonni correction test. *P < 0.05, **P < 0.01. d, e The effects of AC extract on food intake of rats. The rate of food intake before CUMS exposure (D) and after CUMS exposure (E). N = 12 rats for each experimental group. Data represent mean ± SEM. Statistical significance was determined by multiple t-test with Bonferonni correction test. *P < 0.05

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