Fig. 1

The selective effect of AELE on breast cancer cell proliferation using MTS assay. Percent proliferation of cells upon increasing AELE treatment. Bar graph showing the percent proliferation of MDA-MB-231 (a), MCF-7 (b) and Mesenchymal Stem Cells (MSCs) (c) treated with AELE. AELE showed a significant dose- and time- dependent inhibition of MDA-MB-231 cell proliferation and no inhibitory effect on MSCs isolated from rat bone marrow upon increasing AELE concentration. Dunnett’s test was used to compare the different concentrations to the control, and Sidak’s test was used to compare different time points of each concentration. Two-way ANOVA was used to determine the significant differences reported with * indicating a p-value: 0.01 < p < 0.05, ** indicating a p- value: 0.001 < p < 0.01, and *** indicating a p-value: p < 0.001