Pharmacodynamics and pharmacokinetics of a new type of recombinant insulin Lisargine injection

Table 4 Summary of experimental data of autophosphorylation of type A insulin receptor

Samples	N = 1	N = 2	N = 3	Mean ± SEM	P value
Samples	EC₅₀ (nM)	EC₅₀ (nM)	EC₅₀ (nM)	Mean ± SEM	vs. S-Insulin	Lantus vs. Lisargine
S-Insulin	17.5	23.7	12.4	17.0 ± 2.3	/	/
Lantus	12.8	17.2	18.7	17.2 ± 0.9	0.681	/
H-Insulin	15.7	15.8	20.4	18.1 ± 1.0	0.884	/
Lisargine	18.2	11.6	31.3	22.6 ± 4.0	0.725	0.531

IC50 half maximal inhibitory concentration, SEM standard error of mean. S-Insulin Sigma Insulin, H-Insulin Human Insulin injection

ISSN: 2662-7671