Pharmacodynamics and pharmacokinetics of a new type of recombinant insulin Lisargine injection

Table 3 Summary of experimental data of insulin growth factor-1 (IGF-1) receptor binding

Samples	N = 1	N = 2	N = 3	Mean ± SEM	P value
Samples	IC₅₀ (nM)	IC₅₀ (nM)	IC₅₀ (nM)	Mean ± SEM	Vs. S-Insulin	Lantus vs. Lisargine
S-Insulin	132.6	70.5	66.0	78.6 ± 10.8	/	/
Lantus	12.6	12.3	13.4	12.9 ± 0.2	0.023	/
H-Insulin	49.2	52.8	39.2	45.4 ± 2.8	0.123	/
Lisargine	12.5	16.6	10.0	12.6 ± 1.3	0.024	0.897

IC50 half maximal inhibitory concentration, SEM standard error of mean. S-Insulin Sigma Insulin, H-Insulin Human Insulin injection

ISSN: 2662-7671