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Table 1 Summary of experimental data of type A insulin receptor binding

From: Pharmacodynamics and pharmacokinetics of a new type of recombinant insulin Lisargine injection

Samples

N = 1

N = 2

N = 3

Mean ± SEM

P value

IC50 (nM)

IC50 (nM)

IC50 (nM)

vs. S-Insulin

Lantus vs. Lisargine

S-Insulin

0.93

0.82

0.79

0.82 ± 0.02

/

/

Lantus

0.82

0.65

0.30

0.50 ± 0.09

0.180

/

H-Insulin

0.76

0.51

0.49

0.54 ± 0.04

0.058

/

Lisargine

0.69

0.74

0.32

0.52 ± 0.09

0.135

0.990

  1. IC50 half maximal inhibitory concentration, SEM standard error of mean. S-Insulin Sigma Insulin, H-Insulin Human Insulin injection