Skip to main content

Table 3 GRADE evidence profile

From: The effectiveness of Baduanjin exercise for hypertension: a systematic review and meta-analysis of randomized controlled trials

Certainty assessment

No. of patients

Effect

Certainty

No. of studies

Risk of bias

Inconsistency

Indirectness

Imprecision

Publication bias

Baduanjin

Control

Absolute(95% CI)

Cardiovascular morbidity and mortality as possibly influenced by systolic blood pressure

14 (RCT)

Serious risk of bias a

Serious inconsistency b

Serious indirectness c

No serious imprecision

Undetected

532

526

MD 8.52 lower (6.40 to 10.65 lower)

VERY LOW

Cardiovascular morbidity and mortality as possibly influenced by diastolic blood pressure

14 (RCT)

Serious risk of bias

Serious inconsistency

Serious indirectness

No serious imprecision

Undetected

532

526

MD 4.65 lower(2.74 to 6.55 lower)

VERY LOW

Cardiovascular morbidity and mortality as possibly influenced by glucose

3 (RCT)

Serious risk of bias

Serious inconsistency

Serious indirectness

Serious imprecision d

Suspected e

124

124

MD 0.44 lower (0.21 to 0.67 lower)

VERY LOW

Cardiovascular morbidity and mortality as possibly influenced by serum total triglyceride

3 (RCT)

Serious risk of bias

No serious inconsistency

Serious indirectness

Serious imprecision

Suspected

124

124

MD 0.35 lower (0.07 to 0.64 lower)

VERY LOW

Cardiovascular morbidity and mortality as possibly influenced by serum total cholesterol

3 (RCT)

Serious risk of bias

Serious inconsistency

Serious indirectness

Serious imprecision

Suspected

124

124

MD 0.71 lower (0.21 to 1.21 lower)

VERY LOW

Cardiovascular morbidity and mortality as possibly influenced by high density lipoprotein cholesterol

2 (RCT)

Serious risk of bias

No serious inconsistency

Serious indirectness

Serious imprecision

Suspected

54

54

MD 0.29 Higher (0.09 to 0.48 higher)

VERY LOW

  1. CI Confidence interval, MD Mean difference
  2. Explanations
  3. a. Blinding cannot be achieved in participants and investigators
  4. b. High I square
  5. c. Surrogate outcome for cardiovascular morbidity and mortality
  6. d. Recommendation would differ if the upper versus the lower boundary of the CI represented the truth
  7. e. Only few studies and small in size