Fig. 6

The inhibitory effect of Cy-3-Glu (a), Cya (b), GLUT1 inhibitor (c), the combination of Cy-3-Glu and GLUT1 inhibitor (d) and the combination of Cya and GLUT1 inhibitor (e) after 24 h-treatment on MC38 cells. Mitochondrial depolarisation is shown by FACS analysis after the MC38 cells were treated with Cy-3-Glu and Cya for 24 h at 1000 μM and cells were stained with JC-1 (f). Data are displayed as the mean ± S.D. of three independent experiments. *p < 0.05, ** p < 0.01, *** p < 0.001 respect to control cells by ANOVA