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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Protocatechuic aldehyde from Salvia miltiorrhiza exhibits an anti-inflammatory effect through inhibiting MAPK signalling pathway

Fig. 5

The effects of Protocatechuic aldehyde on NF-κB and MAPK pathways in vivo. Sampling from C57 mice, mainly two signal pathways (NF-κB and MAPK pathways) were detected. Effects of protocatechuic aldehyde on the expression of ERK/P38/JNK protein in the MAPK pathway of RAW264.7 cells. Effects of protocatechuic aldehyde on the expression of IκB / P65 protein in the NF-κB pathway of RAW264.7 cells. a The effects on MAPK pathways in vivo. b The effects on NF-κB pathways in vivo. Data are presented as mean ± SD (n = 4). #P < 0.05, ##P < 0.01, ###P < 0.001 vs LPS. *P < 0.05, **P < 0.01, ***P < 0.01 vs controls group

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