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Table 5 Effect of PA flower ethanolic extracts on SGOT, SGPT, CRP, TNF-α, and IL-6 in diabetic rats

From: Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy

Groups/Treatment/Dose
(n = 10)
SGOT
(Unit/L)
SGPT
(Unit/L)
CRP
(mg/dl)
TNF-α
(pg/ml)
IL-6
(pg/ml)
Normal Control/1 ml/kg 66.5 ± 2.0 50.1 ± 1.7 31.6 ± 1.3 32.6 + 1.3 15 + 0.81
Diabetic Control/1 ml/kg 248.6 ± 4.3*** 153.2 ± 2.1***, 94 ± 1.6***, 49.3 + 1.3***, 28.9 + 1.2***,
Diabetic-PA/150 mg/kg 153.1 ± 2.5***, ### 72.2 ± 2.5***, ### 43.4 ± 0.92***, ### 37.3 + 0.97*, ### 16.8 + 0.94a, ###
Diabetic-PA/300 mg/kg 116.6 ± 2.4***, ### 62 ± 1.4**, ### 39 ± 0.96**, ### 34.7 + 0.93a, ### 15.7 + 0.86 a, ###
Diabetic-Met/150 mg/kg 178.4 ± 2.9***, ### 100.7 ± 2.1***, ### 54.4 ± 1.4***, ### 39.8 + 0.84***,### 19.9 + 0.82**,###
  1. Values are expressed as mean ± SEM; n = 10. p < 0.05, p < 0.01, p < 0.001 significant vs. Normal Control, ### p < 0.001 significant vs. Diabetic Control, a; non-significant vs. Normal Control; SGOT Serum glutamic oxaloacetic transaminase; SGPT Serum glutamic pyruvic transaminase, CRP C-reactive protein; TNF-α Tumor necrosis factor-alpha; IL-6 Interlukin-6; PA Plicosepalus Acacia; Met Metformin