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Table 5 Effect of PA flower ethanolic extracts on SGOT, SGPT, CRP, TNF-α, and IL-6 in diabetic rats

From: Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy

Groups/Treatment/Dose

(n = 10)

SGOT

(Unit/L)

SGPT

(Unit/L)

CRP

(mg/dl)

TNF-α

(pg/ml)

IL-6

(pg/ml)

Normal Control/1 ml/kg

66.5 ± 2.0

50.1 ± 1.7

31.6 ± 1.3

32.6 + 1.3

15 + 0.81

Diabetic Control/1 ml/kg

248.6 ± 4.3***

153.2 ± 2.1***,

94 ± 1.6***,

49.3 + 1.3***,

28.9 + 1.2***,

Diabetic-PA/150 mg/kg

153.1 ± 2.5***, ###

72.2 ± 2.5***, ###

43.4 ± 0.92***, ###

37.3 + 0.97*, ###

16.8 + 0.94a, ###

Diabetic-PA/300 mg/kg

116.6 ± 2.4***, ###

62 ± 1.4**, ###

39 ± 0.96**, ###

34.7 + 0.93a, ###

15.7 + 0.86 a, ###

Diabetic-Met/150 mg/kg

178.4 ± 2.9***, ###

100.7 ± 2.1***, ###

54.4 ± 1.4***, ###

39.8 + 0.84***,###

19.9 + 0.82**,###

  1. Values are expressed as mean ± SEM; n = 10. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 significant vs. Normal Control, ### p < 0.001 significant vs. Diabetic Control, a; non-significant vs. Normal Control; SGOT Serum glutamic oxaloacetic transaminase; SGPT Serum glutamic pyruvic transaminase, CRP C-reactive protein; TNF-α Tumor necrosis factor-alpha; IL-6 Interlukin-6; PA Plicosepalus Acacia; Met Metformin