Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy

Table 4 Effect of PA flower ethanolic extracts on TGs, Tc, LDL-c, HDL-c, and VLDL in diabetic rats

Groups/Treatment/Dose (n = 10)	TGs (mg/dl)	Tc (mg/dl)	VLDL (mg/dl)	LDL-c (mg/dl)	HDL-c (mg/dl)
Normal Control/1 ml/kg	103 ± 1.0	81.10 ± 2.12	34 ± 0.88	17.10 ± 0.56	20 ± 0.63
Diabetic Control/1 ml/kg	216.5 ± 1.62^∗∗∗	129.9 ± 1.9^∗∗∗	79.4 ± 1.75^∗∗∗	21 ± 0.85^∗∗	9 ± 0.36^∗∗∗
PA-Diabetic/150 mg/kg	175 ± 1.86^{∗∗∗, ###}	94.5 ± 1.14^{∗∗∗, ###}	50 ± 1.14^{∗∗∗, ###}	18.10 ± 0.56^{a, b}	21 ± 0.97^{a, ###}
PA-Diabetic/300 mg/kg	151.8 ± 1.25^{∗∗∗, ###}	63.2 ± 1.18^{∗∗∗, ###}	40.6 ± 0.92^{∗∗, ###}	15.4 ± 0.45^{a, ###}	30.8 ± 0.71^{∗∗∗, ###}
Met-Diabetic/150 mg/kg	118.4 ± 1.75^{∗∗∗, ###}	59.7 ± 0.95^{∗∗∗, ###}	50.6 ± 1.10^{∗∗∗, ###}	18.3 ± 0.95^{a, b}	19.10 ± 0.76 ^{a, ###}

Values are expressed as mean ± SEM; n = 10. ∗∗ p < 0.01, ∗∗∗ p < 0.001 significant vs. Normal Control. ### p < 0.001 significant vs. Diabetic Control, a; non-significant vs. Normal Control, b; non-significant vs. Diabetic Control. TGs Triacylglycerol; Tc Total cholesterol; VLDL Very LDL; LDL-c Low density lipoprotein cholesterol; HDL-c High density lipoprotein cholesterol PA Plicosepalus Acacia; Met Metformin

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