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Table 3 Effect of PA flower ethanolic extracts on SOD, GSH, MDA, NO, and H2O2 in pancreatic tissue of diabetic rats

From: Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy

Groups/Treatment/Dose
(n = 10)
SOD
(Unit/mg protein)
Catalase
(IU/mg protein)
GSH
(μmole/mg protein)
MDA
(μmole/mg protein)
NO
(μmole/L)
H2O2
(μmole/mg protein)
Normal Control/1 ml/kg 109.9 ± 1.41 9 ± 0.36 65.5 ± 1.16 0.48 ± 0.033 1.045 ± 0.02 10.6 ± 0.40
Diabetic Control/1 ml/kg 83.3 ± 1.37 4 ± 0.36 15.2 ± 1.14 12.9 ± 0.60 0.45 ± 0.02 13.6 ± 0.42
Diabetic-PA/150 mg/kg 93.9 ± 2.09, ### 6.57 ± 0.4, ### 60.6 ± 1.6a, ### 1.55 ± 0,090a, ### 0.31 ± 0.01, ### 11.7 ± 0.42a, #
Diabetic-PA/300 mg/kg 119.4 ± 0.92, ### 7.65 ± 0.27a, ### 64.5 ± 2.07a, ### 0.51 ± 0.027a, ### 0.94 ± 0.02, ### 9 ± 0.36a, ###
Diabetic-Met/150 mg/kg 111.1 ± 1.61a, ### 5.59 ± 0.26, # 63.6 ± 1.31a, ### 1.58 ± 0.05a, ### 0.81 ± 0.02, ### 9 ± 0.37a, ###
  1. Values are expressed as mean ± SEM; n = 10. p < 0.001 significant vs. Normal Control. # p < 0.05, ### p < 0.001 significant vs. Diabetic Control, a; non-significant vs. Normal Control, SOD Superoxide dismutase; GSH Reduced glutathione; MDA Malonaldehyde; NO, Nitrous oxide; H2O2 Hydrogen peroxide; PA Plicosepalus Acacia; Met Metformin