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Table 3 Effect of PA flower ethanolic extracts on SOD, GSH, MDA, NO, and H2O2 in pancreatic tissue of diabetic rats

From: Mechanism of antidiabetic effects of Plicosepalus Acaciae flower in streptozotocin-induced type 2 diabetic rats, as complementary and alternative therapy

Groups/Treatment/Dose

(n = 10)

SOD

(Unit/mg protein)

Catalase

(IU/mg protein)

GSH

(μmole/mg protein)

MDA

(μmole/mg protein)

NO

(μmole/L)

H2O2

(μmole/mg protein)

Normal Control/1 ml/kg

109.9 ± 1.41

9 ± 0.36

65.5 ± 1.16

0.48 ± 0.033

1.045 ± 0.02

10.6 ± 0.40

Diabetic Control/1 ml/kg

83.3 ± 1.37∗∗∗

4 ± 0.36∗∗∗

15.2 ± 1.14∗∗∗

12.9 ± 0.60∗∗∗

0.45 ± 0.02∗∗∗

13.6 ± 0.42∗∗∗

Diabetic-PA/150 mg/kg

93.9 ± 2.09∗∗∗, ###

6.57 ± 0.4∗∗∗, ###

60.6 ± 1.6a, ###

1.55 ± 0,090a, ###

0.31 ± 0.01∗∗∗, ###

11.7 ± 0.42a, #

Diabetic-PA/300 mg/kg

119.4 ± 0.92∗∗∗, ###

7.65 ± 0.27a, ###

64.5 ± 2.07a, ###

0.51 ± 0.027a, ###

0.94 ± 0.02∗∗∗, ###

9 ± 0.36a, ###

Diabetic-Met/150 mg/kg

111.1 ± 1.61a, ###

5.59 ± 0.26∗∗∗, #

63.6 ± 1.31a, ###

1.58 ± 0.05a, ###

0.81 ± 0.02∗∗∗, ###

9 ± 0.37a, ###

  1. Values are expressed as mean ± SEM; n = 10. ∗∗∗ p < 0.001 significant vs. Normal Control. # p < 0.05, ### p < 0.001 significant vs. Diabetic Control, a; non-significant vs. Normal Control, SOD Superoxide dismutase; GSH Reduced glutathione; MDA Malonaldehyde; NO, Nitrous oxide; H2O2 Hydrogen peroxide; PA Plicosepalus Acacia; Met Metformin