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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: In vivo and in vitro safety evaluation of fermented Citrus sunki peel extract: acute and 90-day repeated oral toxicity studies with genotoxicity assessment

Fig. 3

Lack of chromosome aberration by fermented C. sunki peel extract. Chromosomal aberration test was performed using Chinese Hamster Lung cells. Cells were treated with 1250, 2500 and 5000 μg/mL of fermented C. sunki peel extract (FCPE) for the indicated time with or without metabolic activation using the S-9 factor, and examined to identify cells containing aberrant chromosomes. While the positive controls (P7; mitomycin C and P8; cyclophosphamide, black bars) significantly increased the number of cells with chromosome aberration, FCPE (gray bars) did not show a noticeable change compared to the control (white bars) in all tested conditions. *; p < 0.05 when compared to the control by Fisher’s exact test

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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