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Table 2 Effects of the leaf aqueous extract of M. arboreus on ovarian follicle growth and maturation

From: The leaf aqueous extract of Myrianthus arboreus P. Beauv. (Cecropiaceae) improved letrozole-induced polycystic ovarian syndrome associated conditions and infertility in female Wistar rats

Groups

Primary follicles

Secondary follicles

Tertiary follicles

Graafian follicles

Corpora lutea

Cystic follicles

Atretic follicles

NC

3.20 ± 0.49

2.80 ± 0.20

2.20 ± 0.37

2.40 ± 0.24

12.00 ± 1.26

0.00 ± 0.00

5.60 ± 0.51

LTZ

1.50 ± 0.22*

0.80 ± 0.37

1.40 ± 0.24

1.60 ± 0.24

4.75 ± 0.19***

13.25 ± 0.79***

10.60 ± 0.60***

LTZ + CC + MET

5.00 ± 0.32*, ###

4.75 ± 0.37#

6.00 ± 0.45***, ###

3.80 ± 0.58##

10.00 ± 1.14###

2.33 ± 0.18**, ###

7.00 ± 0.45 ###

LTZ + AE 20

6.00 ± 0.32***, ###

5.00 ± 0.32#

3.33 ± 0.18#

5.00 ± 0.32***, ###

9.50 ± 0.50##

3.67 ± 0.36***, ###

7.20 ± 0.37##

LTZ + AE 110

8.00 ± 0.32***, ###

8.80 ± 1.07***, ###

4.00 ± 0.32*, ###

5.25 ± 0.19***, ###

6.20 ± 0.58***

4.00 ± 0.32***, ###

6.60 ± 0.81###

LTZ + AE 200

9.00 ± 0.55***, ###

9.20 ± 1.59***, ###

3.40 ± 0.51##

6.00 ± 0.32***, ###

7.33 ± 0.36**

4.00 ± 0.32***, ###

7.60 ± 0.25##

  1. NC normal control; LTZ letrozole; CC clomiphene citrate; MET metformine; AE leaf aqueous extract of M. arboreus. Results are presented as mean S.E.M., n = 5. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs NC. # p < 0.05, ## p < 0.01 and ### p < 0.001 vs LTZ