|
Groups
|
Primary follicles
|
Secondary follicles
|
Tertiary follicles
|
Graafian follicles
|
Corpora lutea
|
Cystic follicles
|
Atretic follicles
|
|---|
|
NC
|
3.20 ± 0.49
|
2.80 ± 0.20
|
2.20 ± 0.37
|
2.40 ± 0.24
|
12.00 ± 1.26
|
0.00 ± 0.00
|
5.60 ± 0.51
|
|
LTZ
|
1.50 ± 0.22*
|
0.80 ± 0.37
|
1.40 ± 0.24
|
1.60 ± 0.24
|
4.75 ± 0.19***
|
13.25 ± 0.79***
|
10.60 ± 0.60***
|
|
LTZ + CC + MET
|
5.00 ± 0.32*, ###
|
4.75 ± 0.37#
|
6.00 ± 0.45***, ###
|
3.80 ± 0.58##
|
10.00 ± 1.14###
|
2.33 ± 0.18**, ###
|
7.00 ± 0.45 ###
|
|
LTZ + AE 20
|
6.00 ± 0.32***, ###
|
5.00 ± 0.32#
|
3.33 ± 0.18#
|
5.00 ± 0.32***, ###
|
9.50 ± 0.50##
|
3.67 ± 0.36***, ###
|
7.20 ± 0.37##
|
|
LTZ + AE 110
|
8.00 ± 0.32***, ###
|
8.80 ± 1.07***, ###
|
4.00 ± 0.32*, ###
|
5.25 ± 0.19***, ###
|
6.20 ± 0.58***
|
4.00 ± 0.32***, ###
|
6.60 ± 0.81###
|
|
LTZ + AE 200
|
9.00 ± 0.55***, ###
|
9.20 ± 1.59***, ###
|
3.40 ± 0.51##
|
6.00 ± 0.32***, ###
|
7.33 ± 0.36**
|
4.00 ± 0.32***, ###
|
7.60 ± 0.25##
|
- NC normal control; LTZ letrozole; CC clomiphene citrate; MET metformine; AE leaf aqueous extract of M. arboreus. Results are presented as mean S.E.M., n = 5. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs NC. # p < 0.05, ## p < 0.01 and ### p < 0.001 vs LTZ
