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Table 1 The top 20 biological processes enriched by the 54 putative targets

From: Herbal pair Huangqin-Baishao: mechanisms underlying inflammatory bowel disease by combined system pharmacology and cell experiment approach

Term

Count of Proteins

%

p -Value

positive regulation of nitric oxide biosynthetic process

14

25.93

2.12 × 10−23

inflammatory response

20

37.04

1.89 × 10−18

positive regulation of transcription from RNA polymerase II promoter

26

48.15

1.90 × 10−17

positive regulation of smooth muscle cell proliferation

12

22.22

3.09 × 10−17

lipopolysaccharide-mediated signaling pathway

10

18.52

4.01 × 10−16

positive regulation of gene expression

16

29.63

1.99 × 10−15

response to drug

16

29.63

1.76 × 10−14

cellular response to lipopolysaccharide

12

22.22

4.69 × 10−14

response to lipopolysaccharide

13

24.07

9.47 × 10−14

positive regulation of transcription, DNA-templated

18

33.33

1.69 × 10−13

aging

12

22.22

3.15 × 10−12

cellular response to organic cyclic compound

9

16.67

1.11 × 10−11

angiogenesis

12

22.22

8.27 × 10−11

positive regulation of protein phosphorylation

10

18.52

2.04 × 10−10

movement of cell or subcellular component

9

16.67

2.49 × 10−10

response to antibiotic

7

12.96

6.28 × 10−10

negative regulation of apoptotic process

14

25.93

1.12 × 10−9

cellular response to mechanical stimulus

8

14.81

2.36 × 10−9

negative regulation of cell proliferation

13

24.07

2.79 × 10−9

positive regulation of ERK1 and ERK2 cascade

10

18.52

3.53 × 10−9