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Table 7 Major metabolite changes observed in normal control (MC), cisplatin induced (MCIS) and aqueous extract pre-treatment (MAQ) of NRK-52E culture media

From: NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition

Metabolite

δH ppm (multiplicity)

CIS

AQCN + CIS

Alanine

1.48 (d)

1.10***

1.56***

Ethanol

1.17 (t), 3.65 (dd)

0.57**

1.29***

Glucose

5.22 (d)

1.05***

1.01***

Lactate

1.30 (d)

0.93**

1.11***

Pyruvate

3.36 (s)

1.14***

1.26***

  1. ***p < 0.0001, **p < 0.001