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Table 7 Major metabolite changes observed in normal control (MC), cisplatin induced (MCIS) and aqueous extract pre-treatment (MAQ) of NRK-52E culture media

From: NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition

Metabolite δH ppm (multiplicity) CIS AQCN + CIS
Alanine 1.48 (d) 1.10*** 1.56***
Ethanol 1.17 (t), 3.65 (dd) 0.57** 1.29***
Glucose 5.22 (d) 1.05*** 1.01***
Lactate 1.30 (d) 0.93** 1.11***
Pyruvate 3.36 (s) 1.14*** 1.26***
  1. ***p < 0.0001, **p < 0.001