Table 6 Major metabolite changes observed in normal: control (C), cisplatin induced (CIS) and aqueous extract pre-treatment (AQ) of NRK-52E cells extract, ***p < 0.0001, **p < 0.001, *p < 0.05
| Metabolite | δH ppm (multiplicity) | CIS vs C | AQ vs C |
|---|---|---|---|
| Acetate | 1.90 (s) | 0.42** | 0.51** |
| Alanine | 1.46 (d, 7.2 Hz) | 0.70** | 1.16*** |
| Choline | 3.18 (s) | 4.07*** | 2.26*** |
| Creatine | 3.02 (s) | 1.66*** | 1.76*** |
| Ethanol | 1.17(t) | 0.48** | 0.61** |
| Glutamate | 2.14 (m), 2.38 (m) | 0.20* | 0.43** |
| Glycerophosphocholine (GPC) | 3.22 (s) | 0.44** | 0.35* |
| Lactate | 1.30 (d, 6.7 Hz) | 0.42** | 0.92** |
| Lysine | 1.54 (m) | 1.62*** | 0.74** |
| Phosphocholine | 3.20 (s), 3.58 (m), 4.15 (m) | 1.33*** | 1.61*** |